Brain opioid receptor binding in early abstinence from opioid dependence
نویسندگان
چکیده
منابع مشابه
Opioid Receptor Binding in Rat Brain
While the distribution of opioid receptors can be differentiated in the rat central nervous system, their precise localization has remained controversial. due. in part. to the previous lack of selective ligands and insensitive assaying conditions. The present study analyzed this issue further by examining the receptor selectivity of [‘HIDAGO (Tyr-o-Ala-Gly-MePhe-Gly-ol). [‘HIDPDPE (2-o-penicill...
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A methodological approach was established for the study of ligand binding to multiple opioid receptors in slices from rat brain striatum. Specific binding of radiolabeled opiates was resolved from total binding with enantiomers or excess unlabeled ligand. Equilibrium binding of triated etorphine, dihydromorphine, and ethylketocyclazocine, and competitive displacement of [3H]etorphine and [3H]di...
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INTRODUCTION Dependence on opioids is a multifactorial condition involving genetic and psychosocial factors. There are three stages to treating opioid dependence. Stabilisation is usually by opioid substitution treatments, and aims to ensure that the drug use becomes independent of mental state (such as craving and mood) and independent of circumstances (such as finance and physical location). ...
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Anne Morinville,1,2 Catherine M. Cahill,2 M. James Esdaile,2 Haneen Aibak,2 Brian Collier,1 Brigitte L. Kieffer,3 and Alain Beaudet2 1Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada H3G 1Y6, 2Montréal Neurological Institute, McGill University, Montréal, Québec, Canada H3A 2B4, and 3Institute of Genetics and of Molecular and Cellular Biology, National Cen...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 2007
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.bp.106.031120